6BM039 - Clinical Haematology Assignment - University of Wolverhampton

Assignment Task

Your assessment task is to write a report on the given patient case study to include an appraisal of the presentation and results from any laboratory tests, a differential diagnosis and any further tests that would be needed to clarify the diagnosis, a brief summary of the disease biology and an appraisal of a study showing the effectiveness of an up-to-date treatment. You should support your report with citations to scientific articles published in peer-reviewed journals using the Department’s Harvard referencing system

Marks will be awarded for identifying the relevant parameters in any tests carried out so far rather than woodenly commenting on each one, and for interpreting them together rather than as isolated entities. (Note that relevant parameters may include those in the normal range.)

Differential diagnosis

Credit will be given for logical interpretation of the information and formulation of a differential diagnosis, even where this does not necessarily arrive at the “correct” answer. If further tests would be likely to resolve the diagnosis these should be suggested, and an indication of how the results would be interpreted. The appropriateness of such tests should be considered – expensive and time-consuming tests should not be ordered without due consideration.

Disease biology and treatment

A brief summary of the most likely disorder should be given, along with an appraisal of a primary paper that demonstrates the effectiveness of a current treatment. The paper could be of a clinical trial showing improved outcome over previous therapy, an experimental paper showing proof-of-principle in an animal model, cell culture model or phase I trial or other suitable study. You should summarize the aims of the paper, the work they undertook to achieve those aims and how they established it was a success.

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