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  • Research Literature Fail/Pass NA ? information fromrelevant and recentoriginal research orreview articles NA ? Information fromtextbooks or fromMIMS or other drugdatabase only
  • Pharmacodynamics ofthe drugDiscussion ofpharmacodynamics(including: Drug group andother drugs in this group)Mechanism of action,Half-life,Therapeutic range,Onset of action,Peak concentration andtime to clinical effect,Duration of effect.Pregnancy rating, ongoingobservations, tests ormonitoring etc) 25% ? Comprehensivediscussion of thepharmacodynamics ofthe drug.? Mechanism of action? Therapeutic effect? Adverse effects,? Ongoingobservations, tests, ormonitoringetc ? Pharmacodynamicsexplained with sufficientdiscussion ? All parametersgiven with minimalbut acceptablediscussion ? Not allpharmacodynamicalaspects given? Discussion ismissing or does notdemonstrateadequateunderstanding ofpharmacodynamics
  • Pharmacokinetics of thedrug in the motherDiscussion ofpharmacokineticparameters ADME in themother 35% ? Comprehensivediscussion of the drugin the mother? Absorption(administration,bioavailability, firstpass effect)? Distribution (proteinbinding, volume ofdistribution, lipid/watersolubility)? Elimination(metabolism, excretion) ? Maternalpharmacokinetic aspectsgiven with sufficientdiscussion ofpharmacokinetics of thedrug during pregnancy?Absorption? Distribution? Elimination(metabolism, excretion) ? All parametersgiven with minimalbut acceptablediscussion? Absorption? Distribution? Elimination ? Not all maternalpharmacokineticaspects given? Discussion ismissing or does notdemonstrateadequateunderstanding ofpharmacokinetics
  • Pharmacokinetics of thedrug in the placentaDiscussion ofpharmacokineticparameters in theplacenta 10% ? All placentalpharmacokineticaspects discussed andrelated to placentalstructure? Absorption(movement into theplacenta)? Distribution (proteinbinding, transportproteins, fetal tomaternal drug ratio)? Metabolism? Excretion (transfer tofetus, transfer tomother) ? All placentalpharmacokinetic aspectsdiscussed? Absorption? Distribution? Metabolism? Excretion ? All placentalpharmacokineticaspects given withminimal butacceptable discussionof pharmacokineticsof the drug in theplacenta ? Not all placentalpharmacokineticaspects given
  • Pharmacokinetics of thedrug in the fetusDiscussion ofpharmacokineticparameters in the fetus10% ? Comprehensivediscussion of the drugin the fetalcompartment? Absorption(movement into thefetus)? Distribution (proteinbinding, bodycomposition, volume ofdistribution)? Metabolism? Excretion(movement into theamniotic fluid, transferto the placenta) ? Fetal compartmentpharmacokinetic aspectsgiven with sufficientdiscussion? Absorption? Distribution? Metabolism? Excretion ? All parametersgiven with minimalbut acceptablediscussion ofpharmacokinetics ofthe drug in the fetus? Not all fetalpharmacokineticaspects given? Discussion ismissing or does notdemonstrateadequateunderstanding ofpharmacokinetics inthe fetusEffects of the drug in thefetus and breastfeedingneonateSpecific effects of thedrug in the fetus5% ? Comprehensivediscussion of the effectsof the drug in the fetusand breastfeedingneonate ? Fetal effects andeffects on breastfeedingneonate given withsufficient discussion ofpharmacology ? All effects of thedrug in the fetus andbreastfeeding neonategiven with minimalbut acceptablediscussion ofpharmacology ? Not all effects ofthe drug in the fetusand breastfeedingneonate give
  • Presentation (8 minutes)style, quality of the PPTslides, fluency, andsuccinctness,Quality of references &referencing –(APA 7th referencingstyle)Over allocated time: only2 minutes with thepenalty of 1 mark per fullminute 7.5% ? Excellent slides withthe use of Headings andsub-headings, nospelling or grammarerrors, each slidereferencedappropriately? Presentation withclear articulation,proper volume, steadyrate, good posture andeye contact, confidence? Literature referenceshave relevance,authority, currency andcome from high qualityresearch/ reviewSources, ? Good slides with theuse of proficient use ofHeadings and subheadings, adequatespelling and grammar,each slide referencedappropriately? Presentation with cleararticulation and onlyminor variation involume, rate, posture,and eye contact? Literature referenceshave relevance, authority,currency and come fromhigh quality research/review sources ? Minor problems inPPT structure,style, spelling orgrammar errors, eachslide referencedappropriately? Presentation mostlywith clear articulation,variation in volume,rate, posture and eyecontact? Adequateliterature referencesfrom high qualityresearch/reviewsources

 

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