Analytic Approaches in Epidemiology - Nursing Assignment Help

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QUESTION 1: 

A prospective cohort study of psychiatric outpatients with a history of suicidal ideation  was conducted, investigating the effect of alcohol consumption and incidence of  attempted suicide over a follow-up period of 24 months. The data at the end of the  follow-up period for males and females are given below. 

 

Males

Alcohol consumption   Cases   Participants

Light                                5                250

Heavy                              23              250

 

Females

Alcohol consumption   Cases   Participants

Light                                25                250

Heavy                              53                167   

 

Assume no loss to follow-up and that all participants were followed over the follow-up  period. 

Discuss statistical interaction and confounding by sex for the following effect measures 

Risk difference 

Risk ratio 

Odds ratio 

 

QUESTION 2 

Propose a causal diagram of the relationship between alcohol consumption and  attempted suicide, based on the variables provided above. Provide a narrative  description (1 paragraph only) of the causal diagram incorporating findings from your  analysis in Question 1. 

 

QUESTION 3 

Estimate the RR closest to the null value that would be required for a given confounder  (C) (i.e. RRC|suicide) to account for the adjusted association between alcohol consumption  and attempted suicide (i.e. RRalcohol|suicide) in Question 1. 

 

QUESTION 4

The data in the table below are taken from the National Mental Health Survey, a large,  nationally representative cross-sectional prevalence survey estimating 12-month  prevalence of a range of mental health, service use, and disability factors in addition to  socio-demographic variables. Similar questions regarding alcohol consumption and  suicidal behaviour were asked of participants. An extract of the data are given below,  stratified by males and females. 

 

males

Alcohol consumption   Cases   Participants

Light                                31                2885

Heavy                              7                1109 

 

Females

Alcohol consumption   Cases   Participants

Light                                26                4387

Heavy                              04                542  

 

measures:  

Risk difference 

Risk ratio 

Odds ratio

 

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