Highlights
Task:
Instructions
This article is available free of charge. Read the above article and write a 1500 (+1-10%) word essay on the advantages and disadvantages of molecular versus phenotypic bacterial identification methods. You should discuss molecular methods (PCR), MALDI-TOF, and routine phenotypic culture methods in relation to the findings of the paper. The focus of the essay should include speed of the assays and turnaround times, sensitivity and specificity of the methods, technical training and labour intensity, cost implications and assay limitations. This assignment is NOT asking for a long, detailed explanation of the methods. You are asked to compare and contrast the methods and give a critical analysis of the benefits and limitations of each method. Select one or two journal articles to support your discussion of molecular methods, NAATs. Remember, while MALDI TOF looks at molecules it is still a phenotypic method as it is looking at gene products (proteins).
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