BCHM220 - Assignment 1 Group Research Essay

Biochemical Dynamics of Metabolic States during Pregnancy: A Focus on Fed, Fasted, and Starvation Conditions

Each student will be assigned into a group that will research either an altered physiological state or a pathological metabolic state. Each group has a padlet account which will enable students to post information in a variety of formats for the whole group to use. Please ensure that you make significant early contributions of researched information to the group. When you post information on padlet please annotate it with your full name. I will be monitoring student activity on the padlet sites. You can also bounce ideas around on the padlet group sites. The researching of information for your assignment is designed as a collaborative exercise.

Your assignment 1 topic is to examine the biochemistry of fed, fasted and starvation states during Pregnancy.

The Essay

Each individual student will have to submit their own 1500 word essay on his/her main findings.

Your essay should include:

· a brief introduction to the topic, including a one sentence synopsis or argument of the essay. It is critically important that you include an argument in your essay. The presentation of an argument is central to ALL scientific writing and as such forms the foundation of good science. "If you aim at nothing you hit it every time."

· a map and concise but detailed description of the inter-organ flow of metabolites under normal fed-fasted metabolic states and the perturbation due to a specific pathology or altered physiological state.

· explanation of mechanisms involved in regulating the flow of metabolites and energy (e.g. the involvement of pancreatic hormones). Note powerpoint is good for drawing these types of metabolic maps. Submission of hand drawn maps will result in deduction of marks.

· A succinct conclusion paragraph.

· Six references (including at least 2 review scientific articles).

 Referencing Format

•  In-text referencing:
• Single author citation (Green, 2013)
•  Two author citation (Took and Gamgee, 2009)
•  Three or more author citations (Grey et. al., 2005)
•   Bibliographic citation
•  Green, T. (1998) Stubbing of toes is a major source of injuries in hobbits. J. Hobbit Res. 256:1612-1618.
•  Took, P. and Gamgee, S. (2009) Advanced technologies used in hobbit hole design. Arch. Hobbit Invest. 13:81-93.
•  Grey, G., Oakenshield, T. and Baggins B. (2005) Hobbit recruitment techniques for aspiring adventurers. J. Middle Earth 9:345-399.

The map you present in your essay MUST be a compilation of your research groups activity and not copied directly from text book, internet or any other source.

Note: I am looking for you to generate an integrated pathway, inter-organ metabolic map in which the pathways and organs are connected metabolically (be imaginative with the setting out of this map).

HINT: If you make your integrated map the central figure in your essay you can use your paragraphs to explain your central integrated biochemical map under normal fed, fasted and your assigned perturbed physiological or pathological conditions.

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