BIO1010 - Data display, Analysis and Interpretation - Mini Review - Mole Rats - Heterocephalus Glaber - Biology Assessment Answer

Assessment Task:

BIO1010 - Data display, Analysis and Interpretation Biology Assessment Answer

Part A: Data display, analysis and interpretation

The aim of this exercise is to enable you to show your ability to:

•  use Excel to manipulate data and produce appropriate figures to illustrate results
•  incorporate Excel figures into a Word document
•  use Minitab to carry out statistical analyses
•  interpret data and report results in the correct style

Measurements were taken from naked mole rats (Heterocephalus glaber). The variables are body length (L) and skull width (SW), for non-reproductive males, non-reproductive females, reproductive males and reproductive ‘queen’ females. All measurements are in mm. Each pair of body length and skull width measurements were taken from the same individual.

Analyse the data and report the results in the style of the data analysis Methods and Results in sections of a journal paper. Use the information and examples from BIO1010 data analysis practicals to produce graphs and report statistics in an appropriate format.

Part B: Mini Review

 While studying for your degree, you will use many different information sources. One of these will be literature reviews. Literature reviews also called scientific reviews and review articles, are described by Johnson and Scott (p 31) as being a piece of writing that “brings together, in a single article, a synthesis of a large number of individual research papers. The approach of these articles is usually designed to enable someone with some knowledge of the field, but not necessarily at a very detailed level, to derive a picture of the current ideas and developments within that field without having to read all the individual research papers.”

You are required to write a mini review on naked mole rats and cancer. Cancer has never been observed in naked mole rats - what are the suggested reasons for this? You should write a mini review that discusses the current hypotheses behind this phenomenon, all of which should be backed by experimental evidence.

Here are two papers on this topic to get you started (you do not necessarily need to cite these in your final review):

Seluanov A, Hine C, Azpurua J, Feigenson M, Bozzella M, Mao Z, Catania KC, Gorbunova V (2009) Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat. Proceedings of the National Academy of Sciences of the United States of America 106:19352-19357

Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A (2013) High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature 18:346-349

You should decide on a narrative for your mini review and use enough scientific papers to provide evidence support your “story”. You may need to read around the subject before you decide on the final papers to include in your mini review. You need to analyse and interpret the content of the papers you are studying in order to produce a fully integrated account of what they represent collectively.

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