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BIO2108 - The White Blood Cell and Differential Count Assignment
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Assignment Task
Part
A. Will be completed and assessed on the final day of the Residential School.
B. Will be completed following the residential school and submitted by the due date provided on StudyDesk.
Performance of WBC Differential Counts
During the three-day residential school, you will learn and practice WBC differential counting. You will record your “diffs” for ten different blood films and then be assessed on how well you are able to correctly identify different types of WBC, calculate absolute cell counts, and recognise platelet clumps.
Film 1
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
9.01 x 109/L |
4.0-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Comments: |
|||
Film 2
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
23.49 x 109/L |
10.0-26.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
4.0-14.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
3.0-8.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.5-2.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Band neutrophils |
% |
x 109/L |
|
|
Nucleated RBC (NRBC) |
Per 100 WBC |
3-10 / 100 WBC |
|
|
Comments: |
|||
Film 3
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
7.30 x109/L |
4.0-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Comments: |
|||
Film 4
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
6.78 x 109/L |
4.0-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Metamyelocyte |
% |
x 109/L |
|
|
Myelocyte |
% |
x 109/L |
|
|
Comments: |
|||
Film 5
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
21.56 x 109/L |
4.00-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Metamyelocyte |
% |
x 109/L |
|
|
Myelocyte |
% |
x 109/L |
|
|
Nucleated RBC (NRBC) |
Per 100 WBC |
||
|
Comments: |
|||
Film 6
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
18.80 x 109/L |
4.00-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Comments: |
|||
Film 7
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
4.38 x 109/L |
4.00-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Metamyelocyte |
% |
x 109/L |
|
|
Myelocyte |
% |
x 109/L |
|
|
Nucleated RBC (NRBC) |
Per 100/WCC |
||
|
Comments: |
|||
Film 8
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
11.1 x 109/L |
4.0-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Metamyelocytes |
% |
x 109/L |
|
|
Myelocytes |
% |
x 109/L |
|
|
Promyelocytes |
% |
x 109/L |
|
|
Nucleated RBC (NRBC) |
Per 100/WCC |
|
|
|
Comments: |
|||
Film 9
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
4.85 x 109/L |
4.00-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Comments: |
|||
Film 10
|
Parameter |
Result |
Reference Range |
|
|
White cell count |
7.20 x 109/L |
4.00-11.0 x 109/L |
|
|
Neutrophil count |
% |
x 109/L |
2.0-8.0 x 109/L |
|
Lymphocyte count |
% |
x 109/L |
1.0-4.0 x 109/L |
|
Monocyte count |
% |
x 109/L |
0.1-1.0 x 109/L |
|
Eosinophil count |
% |
x 109/L |
<0>9/L |
|
Basophil Count |
% |
x 109/L |
<0>9/L |
|
Comments: |
|||
Introduction : Include relevant referenced background information regarding the role of blood film review in routine haematology and the importance of accurate and timely reporting of results. Remember to link your introduction to the title.
Discussion: Include discussion on the clinical significance of each critical feature listed below, and the possible consequences for the patient if the feature is not identified and reported. Use example(s) of specific associated haematological conditions for each feature.
- Polychromasia: Describe the nature, morphology, and significance of polychromasia, and explain the possible consequences of delayed diagnosis of associated conditions when polychromasia is overlooked.
- Fragmented RBC: Describe the mechanisms by which RBC become fragmented and explain the possible consequences of delayed diagnosis of associated conditions when fragmented RBC are overlooked.
- Spherocytes: Describe the processes that lead to spherocyte formation and explain the possible consequences of delayed diagnosis of associated conditions when fragmented RBC are overlooked.
- Left Shift: Describe the morphology and clinical significance of left shift and explain the possible consequences of delayed diagnosis of associated conditions when left shift is overlooked, particularly in neonates.
- Blasts: Describe the general morphology of blasts and explain the clinical significance of their presence in the peripheral blood and the possible consequences of delayed diagnosis of associated conditions when blasts are overlooked.
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