BIOL122 - Human Biological Science - Medical Science Assignment Help

Assignment Task:

Task:

DIABETES MELLITUS

You must answer all questions below:

Question 1a Explain how both of the following are different in your patient in comparison to a healthy, nondiabetic person:

(a) Insulin synthesis and secretion; and

(b) Insulin binding to its target cells.

Question 1b Explain the benefits of monitoring HbA1c in the management of your person’s/client’s disease.

Question 2a Neuropathy and myocardial infarction are long-term consequences of poorly managed diabetes. Explain why they are more likely to occur in patients suffering from diabetes than in the nondiabetic population.

Question 2b Both metformin and insulin may be used in the management of diabetes mellitus. By making meaningful references to your patient,

(a) Choose the one that is the most appropriate for the treatment of your patient,

(b) Describe the mechanism of action of your choice, and

(c) Explain what makes the drug you selected the most appropriate for the treatment of your patient.

Question 3 Define insulin resistance and explain the link between apple-type obesity and insulin resistance.

5 EXTRINSIC BRONCHIAL ASTHMA

You must answer all questions below:

Question 1 Two of the major pathological changes that affect the airways during an asthma attack are bronchoconstriction and increased mucus production in the airways. By reflecting on the pathophysiology of bronchial asthma, explain how these pathological changes arise in your patient. In your explanation, you are expected the outline the significance of a specific allergen that may trigger an acute asthma attack.

Question 2a The clinical manifestations of an acute asthma attack may include the following signs and symptoms:

GROUP A GROUP B

Cough Airway oedema Hypoxia Increased respiratory rate Wheeze Increased heart rate Tight chest Dyspnoea Choose one clinical manifestation from GROUP A and one from GROUP B and relate them to the underlying pathophysiology for your person. In your answer, explain the link between an acute asthma attack and both signs/symptoms you chose.

Question 2b Salbutamol and corticosteroids are used in the management of asthma. Explain the mechanism of action of these two medications and their benefits in managing your patient’s condition. Question 3 Adequate education of patients suffering from/prone to asthma attacks is important in asthma management. Briefly summarize the advice you would give to your patient in respect to

(a) Corticosteroid administration and (b) Strategies relating to effective prevention and management of their acute asthmatic episodes.

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