BIOL122 - Psychopathology and Pharmacological Management - Biology Assignment

Internal Code: MAS5440

Biology Assignment:

You will have the opportunity to describe the pathophysiology and pharmacological management for a ‘person/client’ who has either type II diabetes or asthma by making a Vodcast - these conditions have been identified as National Health Priority Areas according to the Australian Institute of Health and Welfare. Questions: Part 1: Asthma Vodcast questions  Question 1. Two major pathological changes that occur in the lungs during an asthma attack are: 1) Bronchial smooth muscle contraction 2) Inflammation of the bronchi Explain how these pathological changes arise in your person/client (ie. the pathophysiology). Question 2. The clinical manifestations of asthma include: GROUP A           GROUP B Cough                   Airway oedema Hypoxia               Increased respiratory rate Wheeze                Increased heart rate Tight chest          Dyspnoea Choose ONE clinical manifestation from GROUP A and ONE clinical manifestation from GROUP B and relate them to the underlying pathophysiology for your person. Question 3. The following drugs are used in the management of asthma. 1) Salbutamol 2)Inhaled corticosteroid Choose ONE that is appropriate for your person/client. Discuss why it can be used by your person/client by referring to its mechanism of action.   Question 4. Answer both parts (a) and (b) (a) Exercise can often improve asthma symptoms. Explain whether this could this be the case in your person/client. (b) Explain whether exposure to cigarette smoking (active or passive) could be a trigger or exacerbate asthma symptoms for your person/client Part 2: Diabetes mellitus Vodcast questions Question 1. The following physiological processes are important for blood glucose control: 1) Insulin synthesis and release 2) Insulin binding to target tissues Explain how they are different in your person/client in comparison to a healthy non-diabetic person. Question 2. The following are some consequences of long-term poorly controlled hyperglycaemia: 1) Retinopathy 2) Angina pectoris Explain why they may occur in your person/client. Question 3. The following drugs are used in the management of type II diabetes mellitus. 1) Metformin 2)Insulin Choose ONE that is appropriate for your person/client. Discuss why it can be used by your person/client by referring to its mechanism of action Question 4. Answer both parts (a) and (b) Answer both parts (a) and (b) (a) Insulin resistance can occur in a person with increased abdominal adiposity. Explain the pathophysiological basis for this. (b) Explain why HbA1c has used a measure of long-term control of blood glucose levels and how this the measure will be useful in the management of your person’s/client’s disease.