Highlights
Cholesterol is a critical biomolecule that is present in abundance in the plasma membrane. The structure and function of the molecule have been discussed in this paper to assert the significance of the molecule in the highly dynamic phospholipid bilayers. The plasma membrane is a highly dynamic structure that is significantly impacted by the presence of cholesterol. Cholesterol is responsible for the formation of structures called lipid rafts that are used for cellular signalling and also in the process of membrane fusion. The review provides a succinct summary of how cholesterol molecules regulate the structure and the function of the plasma membrane. The biomolecule influences the permeability, compressibility, fluidity, and the curvature of the membrane. Cholesterol is also important in the process of cell signalling and plays an important role in the process of immune system regulation. The molecule is also essential for the process of membrane fusion and regulation of secretions from the cell.
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