Highlights
The reactions of carbonyl compounds are one of the most important class of synthetically useful reaction in organic chemistry. The carbonyl functional group is also regarded as the most important functional group. This functional group can participate in multiple modes of reactions. The reactions of carbonyls can be broadly classified as the direct nucleophilic addition reactions wherein a nucleophile adds to the carbonyl carbon atom.
The other equally important and versatile family of reactions of carbonyl arise due to the acidity of the alpha-C-H groups. Upon treatment with a base, such compounds are capable of yielding a very useful nucloeophile, known as enolate. The chemistry of enolates are widely exploited for the generation of C-C bonds in various reaction.
2. PROPERTIES OF ALDEHYDE & KETONE
Aldehydes and ketones are polar molecules because the C=O bond has a dipole moment. The polarity makes aldehydes and ketones have higher boiling points than alkenes of similar molecular weight. Aldehydes and ketones are not hydrogen bond donors (they can’t donate a proton); therefore, they have lower boiling points than alcohols of similar molecular weight. Aldehydes and ketones are hydrogen bond acceptors; this makes them have considerable solubilities in water.
Ketones such as acetone are good solvents because they dissolve both aqueous and organic compounds. Acetone is a polar, aprotic solvent.
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