Cellular Mechanisms of Toxicity - Review Writing - Medical Science Assignment Help

Assignment Task

Project proposal requirements:
Email from professor:

1.As your project will now be mostly literature based and more like a critical review, we can have a wider choice of metals. Are there any toxic metals you are particularly interested in? The focus of the critical review should be more towards the mechanisms of toxicity (e.g. cellular mechanisms of toxicity such as oxidative stress) in freshwater organisms (e.g. fish, invertebrates).

The title of the project could be along the lines of Mechanisms of ----- toxicity in aquatic animals (once you have chosen the metal(s) we can fill in the blank)
I will also provide some mock data for you to analyse.
It is probably best to focus on one or two toxic metals, rather than several. You will therefore need to carry out some searches in Pubmed, Web of Knowledge etc. to get an idea of appropriate areas. When you are collecting information it would be a good idea to draw up a table of concentrations, effects and species

2.Your dry project is supposed to be a critical review of the literature, with some mock data provided for analysis. The scope is not restricted to Gammarus pulex, but should include aquatic invertebrates and fish.
Your project proposal is written as if it is going to be lab based. Instead it is mainly literature based, with some analysis of mock data. Hence for experimental methods you should be talking about which search engines you are going to use, the search terms etc. A guide to literature reviews can be found at
https://journals.sagepub.com/doi/pdf/10.1177/2051415816650133Writing a literature review - SAGE Journals310 Journal of Clinical Urology 9(5) into sections that address specific areas or research ques-tions. Next identify multiple sources for your reference material to obtain a more comprehensive collection of
journals.sagepub.com
You are probably trying to concentrate on too many metals, one would be better (though I do agree that in the wild often more than one pollutant is present at the same time. It is important that you consider mechanisms of toxicity, not just report effects observed. For example, if growth rate is reduced, is this due to reduction in feeding, or is something else involved.
Note: The project proposal should be based on the critical review of the literature, consider any one or two toxic metals.

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