CHEM1110: Dr. Leach - Treatment of Cerebral Ischemic Brain Damage - Chemistry Assignment Help

Assignment Task:

Question 1: from Dr Leach
Describe Pharma industry approaches to the treatment of cerebral ischemic brain damage following a stroke.  Your answer should describe the known drug targets based on the current understanding of the mechanisms of cerebral ischemic damage and neuronal cell death as well as approaches to restoring blood flow and stroke prevention.

Question 2: from Dr Swan-Wallis
Please read the following review:
Anti-Amyloid-b Monoclonal Antibodies for Alzheimer’s Disease: Pitfalls and Promise.(Christopher H. van Dyck, 2017)
Use this paper and additional references to critically review the potential of disease-modifying immunological drugs in the treatment of Alzheimer’s disease.

Question 3: from Professor Everett
Describe with examples the two main approaches to personalised medicine based on genetic and metabolic profiling and give examples of the use of each approach

Question 4: from Dr Pecorino
Immunotherapies for cancer have the potential to change the course of many cancers.Critically discuss monoclonal antibodies, checkpoint blockades and chimaeric antigen receptors as strategies for the development of cancer immunotherapies with named examples.

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