Cindy a 62 years Old Female has Recently been Diagnosed with Colorectal Cancer - Medical Science Assignment Help

Assignment Task:

Task:

ASSESSMENT TASK

cindy a 62 years old female has recently been diagnosed with colorectal cancer.
Pathological examination of biopsy from cindy's colonoscopy and excision reveal moderately differentiated Adenocarcinoma of descending colon, stage 3A (Duke’s C).
Discuss the following in relation to this case: Briefly discuss the
Difference between benign and malignant tumours and explain the different stages of cancer
(Approx 250 words) Discuss the pathophysiology of colorectal cancer disease in relation to a
biopsy result of a moderately differentiated adenocarcinoma grade 3 (Approx 250 words) Discuss
ONE of the three pharmacological components of the FOLFOX treatment regime. Link your
discussion to the relevant pathophysiology of bowel cancer (Approx 250 words)

• QUESTION ONE
• Briefly discuss the difference between benign and malignant tumours and explain the different stages of cancer (Approx 250 words) Reflect on characteristics but focus on/relate this to the molecular underpinnings Why/how are benign tumours limited and malignant tumours invasive.
• QUESTION TWO
• Discuss the pathophysiology of colorectal cancer disease in relation to a biopsy result of a moderately differentiated adenocarcinoma grade 3 (Approx 250 words).
• What is adenocarcinoma
• What is moderately differentiated/grade 3 . What does this suggest about the severity/tumourigenesis of cindy’s cancer . Less differentiated = more genetic mutations = more anaplastic . Relate back to benign vs malignant
• QUESTION THREE
• Discuss ONE of the three pharmacological components of the FOLFOX treatment regime. Link your discussion to the relevant pathophysiology of bowel cancer (Approx 250 words) Must identify all three . Choose ONE to discuss in detail. Include mechanism of action (in your own words)
• How this impact the underlying pathophysiology/how this impedes cancer growth .
• Very briefly mode of administration and side effects . Focus on the molecular interactions and relate this back to the pathophysiology.
• Additional lnformation
• After consultation with the medical oncologist, a treatment regime is put into place for cindy.
• Her treatment includes FOLFOX6: Oxaliplatin, Leucovorin (in oncology over 4 hours), and Fluorouracil (over 2 days via a pump at home). Her cycle of treatment is every 14 days and 12 cycles of treatment recommended.
• Pathology tests are mostly unremarkable except for Hb- 110 g/L and CEA- 5.5mcg/L.
• No introduction or conclusion is needed
• Only use short and succinct headings for each section
• Do not copy and paste the essay question
• Answer each section as if it were a short answer question
• Please use 12 point, 1.5 spacing, normal margins
• Times New Roman or Cosmic Sans is preferred
• Use clear language
• Use concise sentences – don’t ramble on for 4-5 lines. Be specific, get straight to the point.

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