Highlights
Task:
Ischaemic stroke affects a growing number of people each year and is expected to continue to rise as our population ages. As ischaemic stroke frequently results in significant morbidity and mortality there remains a need to find ways to treat stroke injury. Despite extensive understanding of the mechanisms involved in cellular death following ischaemic injury there are still few therapeutic strategies available clinically.
Report topic: Why is it drugs targeting the ischaemic cascade* have been unsuccessful in trials?
You should cite a specific example of a target and drug that have been trialled, together with the outcome (150-200words) followed by a general discussion of the problems that have been encountered when targeting the ischaemic cascade therapeutically (250-350 words).
* – your drug must act on a target within the ischaemic cascade
Case reports
Each student will prepare an individual report (500 words). Your report must be prepared individually, written in your own words, and be properly referenced in author-date style. We expect you will use several references in preparation of the report. You are welcome to use the reference given in the notes but are expected to add at least three more references to support your discussion.
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