Highlights
Internal Code: MAS 4473
Questions: 1. Discuss THREE different factors that would have contributed to the emergence of bacterial resistance to ciprofloxacin. Support your answer with suitable examples. 2. What measures do you think the government/regulatory agencies should take to prevent further increase in bacterial resistance to ciprofloxacin. Using suitable examples, discuss how such measures can be implemented in various countries where bacterial resistance to ciprofloxacin is high. 3. A. Describe a method (other than the dissolution method; the one you used in week 1) which can be used to extract ciprofloxacin from 500 mg ciprofloxacin tablet. B. Discuss two advantages and two disadvantages of the method you describe above to the method you used in week 1. 4. A. Briefly discuss why did you use 10% of acidic acid to dissolve a tablet containing 500 mg of ciprofloxacin. B. Name two solvents (other than 10?etic acid) that can be used to dissolve a tablet containing 500 mg of ciprofloxacin. C. Would you have used another type of solvent to dissolve a tablet containing 750 mg of ciprofloxacin? Yes or no and why? 5. A. What was the amount of ciprofloxacin you found in a tablet that was used to prepare 50 ?g/ml of ciprofloxacin. B. Provide a brief summary of the method you used to determine the amount of ciprofloxacin present in a tablet containing 500 mg of ciprofloxacin.
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