CSE 572: Data Mining - IT Computer Science Assignment Help

Assignment Task

Project 1: Extracting Brain boundaries from rs-fMRI data

Purpose

In this project you will extract the brain boundaries from the resting state functional magnetic resonance imaging (rs-fMRI) scans

Objectives

Students will be able to:

• Extract brain slices from the data set.
• Extract the brain boundary (periphery) from those slices

Project Description

In this project we will work on rs-fmri data. rs-fMRI is a functional magnetic resonance imaging which is done to evaluate the functional connectivity in the brain networks when the patient is in resting state. Patient’s brain evaluation is done based on the blood consumption activations (shown as red clusters in figure 1) in different regions of the brain. These clusters reflect the changes in brain’s activity which are driven by the active areas of human body. The fMRI data is usually a 4D data and it is further decomposed into spatial independent components (ICs) using MELODIC software. In this project, you will be provided with a patient’s rs-fMRI scan’s spatial independent components (ICs), which are nothing but the images like Figure 1. These images will show the brain changes over a period of time. A patient usually has 100 such images and the red cluster’s locations will differ in all these images based on the current active part of the body.

Directions

Dataset:

You will be given one patient’s dataset which will contain approximately 100 spatial ICs images of that patient’s rs-fMRI scan. All the scans will look like figure 1 (except the blood activation (red/blue clusters) part).

Analysis Procedure:

Given the spatial images of patients, your task will be divided into two parts:

a) Brain slice extraction: Given a spatial IC, automate the brain slices extraction process. For example, the IC in figure 1 will have brain slice images like figure 2. So, if a patient has N such images, your task is to automate the slice extraction for all the N images.

b) Brain boundary extraction: Once you have extracted the brain slices, the next task is to extract the boundary of the brain in every extracted slice (will be discussed in class).

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