Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches - Medical Science Assignment Help

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Assignment Task

Please read the attached paper and then answer the following questions:

1. Describe the design of microRNA switches used to purify endothelial cells, hepatocytes, and insulin-producing cells from a human pluripotent stem cell.

2. List the requirements that allow the isolation of cells of interest without sorting.

3. What are the benefits and limitations of miRNA switches?

 

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