Highlights
This matter relates to a 50-year male (weight 100 kg) who was found dead in his unit at midnight. He was last seen alive the previous day. An autopsy was performed some 7 days after being admitted to the mortuary.
He was known to be a drug user, mainly “ice” and other illicit drugs. Other drugs were also found in the house included diazepam, citalopram and zolpidem. The autopsy was largely unremarkable. His heart was slightly enlarged and showed up to 50% occlusion in his coronary arteries. Toxicology analysis revealed the following drugs:
Questions: Please answer the following questions in a medico-legal style – this is a requirement. An example of a medico-legal report is available on moodle.
1. Given the autopsy was unremarkable, did his drug use contribute or cause his death? What other information is useful?
2. What is the most likely source and pharmacological effects of diazepam?
3. What is the most likely source and pharmacological effects of citalopram?
4. What is the most likely source and pharmacological effects of zolpidem?
5. What is the most likely source and pharmacological effects of methylamphetamine?
6. Please discuss the significance of the hair results. How is this information useful?
7. What considerations are important for interpreting postmortem toxicology results? Does the postmortem interval affect drugs concentrations? If so how?
8. Any other comments you wish to make that are relevant to an expert opinion in this matter.
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