Genetic Cancer - Disease: Lobular Breast Cancer - Nursing Assignment Help

Assignment Task:

From these 3 researchers’s about breast cancer 11 points was found:
1. The artifice presented by (Kutasovic et al., 2020) indicated that the region of gene mutation in the context of breast cancer. 
2. The single nucleotide variants (SNV)  in the case of breast cancer have a quite low number of SNV as mentioned in section 2 of the article published by  (Kutasovic et al., 2020).  
3. The study indicated that there is a minimum of 147 genes that are considered as the cancer-driving gene.  
4. Invasive lobular carcinoma (ILC) is involved with impairment in the function of the epithelial cell adhesion complex involving E-cadherin and its binding partners β-catenin and P120-catenin. E-cadherin is encoded by the gene CDH1. 
5. Sub-clonal driver mutation in TP53, PIK3CA, PTEN, MYC amplification as mentioned in the third section of the article published by (Kutasovic et al., 2020). 
6. The article published by (Field et al., 2015) tracked antibody interaction for the identification of cancer. 
7. The article indicated that in order to identify the antibody produced by specific antigen CBA/ca female mice were infected with LDV(Field et al., 2015). 
8. The result of the articles indicated that by conjugating human POSTN to OVA and introducing it to the mice it produced a rare antibody against a rare human protein that would be helpful in the identification of cancer(Field et al., 2015).  
9. The study conducted by (Pereira et al., 2016) indicated that the researcher's 173 genes were primarily attributed to breast cancer. 
10. There was a list of Mut-driver genes that have been identified as the oncogenes that were introduced in the study for the comparison of the lab sequenced material (Pereira et al., 2016). 
11. The study indicated that there is a variation in the mutation pattern of the Mut-driver gene as they provide somatic gene deregulation(Pereira et al., 2016).

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