Highlights
Case Study:
George (He/Him) is a 22-year-old-man diagnosed with bipolar disorder 6 months ago. On admission to the Emergency Department, George stated that he has taken six times the usual dose of his lithium carbonate immediate release (6000mg) over the last two days.
Medical records data indicate that subsequent to lithium carbonate overdose George has developed polyuria, polydipsia, proteinuria, and hypovolemia and has now been diagnosed with acute renal failure.
Questions:
a) Explain why George has developed polyuria, polydipsia, proteinuria, and hypovolaemia following overdose with lithium carbonate.
b) George must undergo haemodialysis to help stabilise his condition. Considering what you know of normal renal function, propose how haemodialysis replaces kidney's function.
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