Highlights
Learning Outcomes of this assignment:
• 1: Explain the aetiology and pathophysiology of common nutrition-related diseases
• 2: Search, interpret and critically evaluate scientific publications on the relationship between diets and nutrition-related diseases
•3: Synthesize current scientific knowledge on the prevention of nutrition-related diseases and produce reports for a professional and lay audience
Part 1: Review and describe the link between obesity and inflammation.
The basis of this link is discussed within the first lecture and associated resources. Within part 1 you are asked to briefly review the underlying pathogenesis linking obesity with chronic low grade inflammation and metabolic dysfunction. In your brief review, you should highlight 4-5 important biomarkers that may be modulated in obesity-induced inflammation, such as specific cytokines or adipokines, C-reactive protein, macrophages and reactive oxygen species. Hint: Consider which biomarkers might be modulated by a Mediterranean Diet (Part 2).
Part 2: Provide evidence on the effectiveness of managing obesity-related inflammation with a Mediterranean diet
Within part 2 you are asked to provide evidence as to whether adopting a Mediterranean diet by an obese person can beneficially modulate inflammation-related biomarkers, particularly those described in part 1. Evidence from studies in individuals with obesity is preferable. Regardless of the strength of evidence available in obese humans, you are also asked to provide 4 – 5 evidence- based nutrition-related recommendations for how an obese person may improve markers of inflammation. Make your recommendations realistic and safe for the individual. Remember, the aim is to help the health professional help their patients, and therefore the recommendations need to be practical.
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