Implement the Needleman and Wunsch Algorithm - Report Writing Engineering Assignment Help

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Assignment Task:

Homework assignment (by March 31st)
Implement the Needleman & Wunsch algorithm, including the backtracking. 
Input: two sequences
Output: their global alignment Assignment grading: 
Implementation of the dynamic programming matrix: 1.5 points 
Implementation of the traceback: 0.5 point
 Submission by the deadline: 0.5 points 
Bonus assignment: implementation of the Smith & Waterman algorithm: 0.5 points
You can use any scoring scheme. 
The code should be written in a way that allows to easily change the score assigned to matches, mismatches or gaps 

  • Be careful with the indexes used to iterate through the matrix and through the sequences 
  • The user should be able to pass sequences to the software without having to edit the code (e.g. from the command line, from a file, or using interactive input). If you use the Python IDLE, try to find a way to do that 
  • The traceback can be implemented in different ways; you can recompute the optimal path on the fly from the last cell, but the simplest is to create another matrix, whose cells contain symbols or labels (e.g. UP, LEFT, DIAG)
     

 

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