Laboratory Techniques and Their Application Assignment

Assignment Task

Introduction

Give an outline of the work that you did that includes:

• Carrying out a chemical reaction to produce the solid product aspirin using reflux and vacuum filtration
• Melting point test on the impure (crude) aspirin
• Purification of the aspirin by recrystallisation
• Thin layer chromatography (TLC) of aspirin samples
• Melting point of purified aspirin
• Mixed melting point

Scientific Principles

Explain the scientific principles (What is a melting point? How does chromatography work? How does recrystallisation work? Etc.), behind the stages of your practical given above. Give references to sources of information that you use at the end of your report

Conclusions

Draw conclusions about the purity of the aspirin you made based on the results of your melting point tests and the TLC result

Identify factors that affect the yield (how much you make) and purity of aspirin in your laboratory preparation and analyse how significant these factors are.

Industrial Manufacture and Testing

Research and describe the industrial manufacture (scale, equipment, raw materials) and testing of aspirin (GC or HPLC).

Comparing Laboratory Preparation and Industrial Production

Compare the laboratory and industrial manufacture and testing of aspirin, explaining principles, similarities and differences in the equipment and techniques used. Remember that the production of a chemical on a large scale is different than in the laboratory

Factors that Affect Yield and Purity

Analyse how relevant the factors you have identified as affecting yield and purity are in the industrial manufacture of aspirin and in ensuring scalability. Scalability means how well you can make larger amounts of aspirin by making the equipment larger etc.

Determining Purity

Analyse whether melting point measurement, mixed melting point measurement and thin layer chromatography are effective ways to assess whether an organic solid is pure and explaining whether other methods used industrially (GC or HPLC) are more effective.

This Engineering has been solved by our PHD Experts at My Uni Paper.