Highlights
Q 1. Microbiome metabolism plays an important role in cancer. Using colon cancer as a model design a therapeutic strategy by modulating the microbiome metabolic profile. You can refer to research articles. Please use citations wherever applicable. 10 points
Q2. Does microbiome have any role to play in the progression and disease outcome of COVID-19? You can refer to research articles. Please use citations wherever applicable. 10 points
Q3. Antibiotics often fail to treat recurrent Clostridium difficile infections. In such cases, FMT is usually the therapeutic strategy of choice. However, FMT sometimes has untoward effects on the recipient. C. difficile is often resistant to bacteriophages. In such circumstances design an alternative strategy to control recurrent C. difficile infection. 10 points
Q4. Each individual carries their own microbiome signature. Map out the host-microbiome communication encompassing meta-transcriptome, glycome, proteome and metabolome in terms of hepatocellular carcinoma. 10 points
Q5. The current trend of personalized medicine focuses mainly on the host genome. For microbiome dysbiosis treatment, often a “one-size-fits-all” approach is taken and universal probiotic supplements are prescribed. What will you do to design a completely personalized medicine profile for a person suffering from coronary artery disease? 10 points
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