Mycobacterium Marinum Infection Case Study - Medical Science Assignment Help

Assignment Task

Case Study One:

A 63-year-old Mara presented to an outpatient clinic with an 8-week history of nodules on her arms. She recalled cutting her thumbs while cleaning fish that she had purchased at a seafood market in preparation for a meal, and the lesions began to develop 6 weeks later. She had no fevers. She also has no prior significant medical history.

Physical examination at the current clinic revealed painful pink nodules and ulcerations with a haemorrhagic crust on both arms. A biopsy specimen was obtained and revealed multiple granulomas. Cultures grew Mycobacterium marinum, a nontuberculous mycobacterium that is found in aquatic environments. Infections typically result from exposure to contaminated water when there are breaks in the skin.

The patient received treatment with moxifloxacin, rifampin, and clarithromycin for 6 months. She had complete resolution of the infection. At a follow-up visit 1 year later, the nodules had resolved but scarring remained.

Questions:

a) Considering that Mara has developed skin nodules following Mycobacterium marinum infection, propose why nodules have developed and remained localised only to hand in this case study?

b) Explain what is meant by what is ulceration and why it might have occurred in this case?

c) Propose why the physician would describe three different antibiotics in this case for 6 months?

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