NEUR 101 : Introduction to Neuroscience Neurophysiology Problem Set - Science and Maths Assignment Help

Assignment Task:

Task:

Membrane Potential
1. Use the Nernst equation to calculate the equilibrium potential for Na+, K+ and Cl-.
E Na+ = ________________
E K+ = ________________
E Cl- = ________________
2. Use the Goldman equation to calculate the resting membrane potential of this neuron (we will only consider Na+, K+ and Cl-, although other ions do make minor contributions to resting membrane potential). For this neuron, assume the relative permeability to N+ is
0.04, to K+ is 1.0, and to Cl- is 0.5.
Resting Membrane Potential = ________________

3. Indicate whether the following ions are at equilibrium when the neuron is at its resting membrane potential by placing a check in the correct column.
Ion At
Equilibriu
m

Not At
Equilibriu
m

Na+
K+
Cl-
4. Explain your answers for question 3. What has to be the case with respect to the membrane potential as compared to the equilibrium potential of an ion for that ion to be at equilibrium?

5. At the resting membrane potential, indicate whether the following ions will enter or exit the cell, or whether there will be no net movement, by placing a check in the corresponding column. For this question, assume that the resting neuron is permeable to all three ions due to the presence of leak channels.
Ion Enter Exit No
Movemen
t

Na+
K+
Cl-

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