Neurologist - Significantly Different - Effective Medication - Effective Medication - Case Study

Assignment Task:

Neurologist - Significantly Different - Effective Medication - Effective Medication - Case Study 

Question 1. Prevalence rates for multiple sclerosis (MS) vary across the globe. Assuming that in a population from the south of France MS prevalence is 62 per 100,000, but in Scotland, it is 205 per 100,000, are these given prevalence rates significantly different? You must detail exactly how you arrive at a probability associated with these rates and explain why you are performing the analysis using your chosen strategy. 
Question 2. In a clinical trial of a new monoclonal antibody with immune-modulatory properties, patients meeting assessed criteria are randomized to two groups - new treatment/ no treatment with standard care and ending up with a total participation of 400 patients. Their disability at a 6 month and 1 year and 2-year time point follow-up was measured by a neurologist in all the patients using the expanded disability scale for MS patients.

Question 3. In a small group of Parkinson’s patients, all with deep-brain electrode implantation, movement problems were quantified for each patient with their normal, effective medication using a key-board tapping task, first with the electrode switched off and then subsequently with electrode activation at the most efficacious setting for each individual.

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