NURS2007: Pathophysiology and Pharmacology How Does Ageing Impact the Process of Pharmacokinetics - Medical Science Assignment Help

Assignment Task:

Task:

QUESTION 1 Approx. 500 words 20% How does ageing impact the process of Pharmacokinetics? In your answer, you need to address ADME and potential adverse effects. Many elderly patients take multiple medications. Briefly, what are some of these patients at risk of and what advice would you give to an elderly patient regarding this?

QUESTION 2 Approx. 500 words 20% You are the nurse looking after Harry Tharrie, a 44 year old Indigenous man. He is in hospital due to acute glomerulonephritis. On assessment, Mr Tharrie is lying flat in bed, he has bilateral pitting oedema, notable periorbital oedema, pale shiny skin, his blood pressure is 160/94, heart rate 110, respiratory rate 30 bpm, and crackles noted on auscultation.

• Demonstrate your understanding of the pathophysiology of acute kidney injury and link it to acute Glomerulonephritis.
• Link 2 signs Mr Tharrie is experiencing with the pathophysiology of his condition. • What is a basic priority nursing care/intervention you would implement immediately upon meeting Mr Tharrie? Please provide rationale with your answer.

QUESTION 3 Approx. 500 words 20% Ms Polly Wallie is a 19 year old woman studying physiotherapy at university. She drinks a lot of coffee and diet sodas and often has just fruit (apples/oranges) throughout the day. She presents at the GP with dysuria, urgency and polyuria and is febrile at 37.8o C. Her urine sample is ‘pink’ with visible sediment. She is diagnosed with a urinary tract infection.

• Education is part of your role. How do you explain to Polly what it is about the pathophysiology of a urinary tract infection, that is causing her symptoms?

• Polly is keen to do anything to reduce her symptoms. Based on this case study, what else does Polly need some nursing education about and why? Provide evidence based rationale with your answer.

• Identify what the first line medication is for a urinary tract infection and explain how this will work (Pharmacodynamics). (*Note: Doctors prescribe, you are simply being asked to identify generally, what is the first line medication)

QUESTION 4 Approx. 500 words 20% Kevin Bevyn presents to the hospital again with abdominal pain– he has had recurring bouts for years. On assessment he tells you he has persistent diarrhoea (liquid but some soft stools, no notable blood in the stools), and pain to his right lower abdominal area and he states it feels “really sore”. Mr Bevyn further states he has lost some weight in the last couple of weeks and a recent blood test indicated he has anaemia. Mr Bevyn is prescribed Sulfasalazine; further investigation is underway for Inflammatory Bowel Disease. • Which of the two conditions studied, do you think it is likely Mr Bevyn will be diagnosed with? Please link symptoms to the pathophysiology to support you answer. • Discuss your understanding of 1 (one) of the signs in this case study linking it clearly to the pathophysiology. • Explain what this medication is and how it will improve Mr Bevyn’s condition. Is there any nursing education you may need to give when administering this medication?

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