Describe the context of the case and explain its relevance and importance.
Describe whether the case is unique. If not, does the case have an unusual diagnosis, prognosis, therapy, or harm?
Is the case an unusual presentation of a common condition? Or an unusual complication of a disease or management?
CASE DESCRIPTION
Report the case in sequence.
Describe the history, clinical presentation, and investigations adequately. What was challenging about the case (e.g., diagnosis or management)?
Highlight how the laboratory investigation added to the clinical management/prognosis. What was novel or unusual about the laboratory investigations?
Describe the outcome adequately. How was the outcome related to the laboratory investigation? What was the role of the pathologists/scientists/technologists?
DISCUSSION
Discuss the rationale for decisions that were made and the lesson from the case.
Report a literature review of other similar cases. Describe how this case is different from those previously reported.
Describe the instructive or teaching points that add value to this case. Does it demonstrate a cost-effective approach to management or an alternative diagnostic/treatment strategy? Does it increase awareness of a rare condition?
Explain the rationale for reporting the case. What is unusual about the case? Does it challenge prevailing wisdom?
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