Highlights
Task:
Read the case studies below (endocrine or musculoskeletal), choose one case study to and discuss the pathophysiology of the condition. You must use academic writing and reference your work using APA referencing. Please do not use bullet points, use well-structured paragraphs, ensure you have edited the text and read it again to avoid spell and grammar mistakes before your final submission.
Case Study 1
Sharon Munroe, 26 year old caucasian female, has a history of Polycystic Ovarian Syndrome (PCOS) for the past 6 years. Medical history includes, cessation of menses several years ago, 20 kg weight gain over the past 5 years, increasing hirsuitism, acne and 2 previous miscarriages and infertility.

You begin a full physical assessment of Sharon. Here is some of the information you collect:
? Sharon is 172 cm tall and weighs 96 kg, giving her a BMI of 32.
? Heart sounds are normal: S1 and S2 heard clearly
? Lung fields sound clear to bases
? Abdomen soft, no masses, bladder non-palpable
Case Study 2
Mr Kim Liu is a 28-year-old Korea man (UR number 527991) who was brought in by paramedics after a motor vehicle accident. He does not speak any English. He suffered an open fracture of the left tibia and fibula and head injury- laceration left temporal area. He has left upper quadrant pain, and a seatbelt mark along his left shoulder, neck and chest. He has a laceration left temporal area. Through an interpreter, it is determined that he is confused to time and place, but remembers his name. He has no known allergies and he has significant pain-9 out of 10-despite intravenous morphine given by the paramedic on site. His observations are as follows:

A chest x-ray suggests some stable rib fractures and leg x-rays reveal crush injuries and comminuted fractures of his left tibia and fibula. An abdominal CT demonstrated a splanchnic haematoma. Mr Liu is going to theatre shortly for an open reduction and internal fixation (ORIF) of his left leg fractures and, depending on his haemodynamic stability, he may also have a laparotomy for the splanchnic haemorrhage.
Discuss the following in relation to the selected case:
? Pathophysiology
? Diagnostic assessments used to diagnose the condition
? Pharmacological management of the condition
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