Research Methods and Data Management - Engineering Assignment Help

Assignment Task

Answer TWO questions
Q1. Answer ALL parts
(a) Measurement of the concentrations of the antibiotic amoxycillin in the plasma of some burns patients 4 hours after dosing gave the following results, all in micrograms per ml: 34, 30, 32, 34 and 74
(i) What is the mean of these data in micrograms per ml:

(ii) What is the median of these data micrograms per ml:

(iii) Is the mean or the median a better descriptor of the central tendency ofthe data and why?

(b) The Wilcoxon signed rank test estimates of a set of data belong to a particularpopulation of data. It is calculated using the following procedure: 1; Compute theresiduals for the experimental values minus the established population medianvalue. 2; Arrange all of the residual values in order of magnitude. 3; Rank all thevalues, including their sign.

4; Sum the positive and negative ranks separately.
5; Compare the lower of the two figures with a Wilcoxon tabulated statisticderived from binomial theory: if the modulus of the lower calculated value is lessthan, or equal to the tabulated value the null hypothesis is rejected.The median drug concentration in an oncology drug formulation is 92 mg/ml. Anew sterile formulation is tested to see if the same drug concentrations can be
The new formulation gives drug concentrations of: 100, 79, 98, 102, 87, 116 and 101 mg/ml

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