Highlights
(a) Make the table of contrast (a table of plus and minus signs from which all the main effects and interaction effects be calculated).
(b) Calculate all the main and interaction effects. Show the steps of your calculation and only run software to check your answer.
(c) Assuming the three-factor and higher order interactions to be noise, compute an estimate of the error variance of the effects. Show the steps of your calculation and only run software to check your answer.
(d) Based on your results from Question 1(b) and (c), which of the estimated effects are likely to be the real effects rather than noise? Why? How would you interpret each of the real effect(s)? Show your interpretation graphically
(e) Assume that the present conditions of operation are 1=5%, 2=40%, 3=10 rpm, 4=180F. Make recommendations of better operation conditions to reduce the impurity.
(f) Assume your conclusions from Question 1(d) remain valid for operation conditions beyond the range enclosed by the two specified levels of the four factors. If you are able to conduct a few more experiment runs, describe how you would set and/or vary the four factors in the additional experiments so that, with as few experiments as possible,
i. You may confirm/ further investigate each of the real effects found in Question 1(d), and
ii. You could most likely find even better operation conditions than your answer to Question 1(e).
Task: 2
Estimate the error variance of the effects.
A chemist used a 24 factorial design to study the effects of temperature, PH, concentration, and agitation rate on yield (measured in grams), without replicated runs. If we know the standard deviation of an individual observation is 6 grams, what is the variance of the temperature effect? Hint: use the basic properties of variances of random variables.
Task: 3
Application of response surface method.
The data table below came from a tire radial run-out study. Lower run-out values are desirable.
The factors under study were:
• 1 x = Post-inflation time (minutes),
• 2 x = Post-inflation pressure (psi),
• 3 x = Cure temperature (0F),
• 4 x = Rim size (inches), and
The response variable was:
• y = Radial run-out (mils).
(a) Suppose you want to fit a second-order polynomial model to the data. Write the equations for least square regression in vector/matrix form. Define all the variables in your equation and specify the dimensions of each. Write down the matrix of independent variable values, X . Hint: a second-order polynomial model can be written as
(a) Analyze the data to obtain your best model:
i. Describe your approach and steps of analysis.
ii. Report your model expression, the overall goodness-of-fit (e.g. ANOVA, esp. Rsquare and Adjusted Rsquare), estimated parameters, and their significance results (t-ratio or p-value).
Hint: fit a second-order polynomial model by stepwise least square regression with each of the two responses. Take the logarithm of filtration time to fit a better model.
(b) Based on your model, draw contour diagrams for yield and filtration time.
(c) Find the settings of 1 x and 2 x within the range enclosed by the experiment design levels that give
i. The highest predicted yield, and
ii. The lowest predicted filtration time.
Hint: optimize each response separately. If you use an analytical method, you should check whether the true maximum/minimum condition is satisfied.
(d) Specify the optimal set of conditions for 1 x and 2 x that will simultaneously give high yield and low filtration time. At this set of conditions what field color and how much crystal growth would you most likely expect?
Hint: Give a best approximation of the optimal condition, either graphically or using a more formal analytical approach.
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