Highlights
There are currently 3 COVID vaccines available within the U.S. For this exam, reflect on the elements of disease control that need to be addressed for a successful deployment of these vaccines to impact COVID transmission.
Design a control plan around the results from the early Phase 3 COVID vaccine studies. Please refer to the initial Phase 3 results from Pfizer [1] and Moderna [2] and the recent FDA VRBPAC meeting to review the Emergency Use Authorization application [3]. Considering initial COVID vaccines are currently only proven to prevent symptomatic or severe disease, what is the plan to mitigate transmission until herd immunity is achieved?
Think through these questions while formulating your response: How do we engage at-risk populations? Are there notable groups to exclude from vaccination at this time? How should vaccine non-compliance and potential failure be addressed? What messaging should occur to reduce vaccine hesitancy? Are there any lessons from the US context that would apply to LMIC settings? Finally, what does “success” or the “new normal” look like? What metrics need to be met to know when we get there (coverage, case counts, deaths, etc.)?
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