Value-Based Pricing - Price Negotiations - Internal or External Reference Pricing - Economics Assignment Help

Assignment Task:

Part A:
Define value-based pricing in health care. What are its advantages and disadvantages over other pricing schemes such as price negotiations or internal or external reference pricing? In what circumstances might value-based pricing be considered inappropriate?

Part B:
With reference to your in-class group work on the paper by Garrison L et al (2019) on the cost-effectiveness of adding  pertuzumab to trastuzumab and chemotherapy in the management of human epidermal growth factor 2-positive (HER2+) breast cancer, critically appraise the paper under the following questions 

1. Are comparators and outcomes well described considered in this study? Do the authors explain their modelling choices and could a different/ more complex Markov model or type of modelling have been used?

2. Around which variables is there most uncertainty and what does the probabilistic sensitivity analysis say about the overall uncertainty surrounding the results? What are the implications of this uncertainty for study findings?

3. How is discounting used? How would changes in the discount rate impact results if there is no sensitivity analysis around discount rates?

4. Where is the quality of life data elicited from? Patients, experts or the general public and from what setting. Does the source or type of quality of life data impact the strength of findings or introduce a bias?

5. What additional information would you want to have apart from this study to make a recommendation?

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