What Protein of the RTC Complex is Targeted - Medical Science Assignment Help

Assignment Task

Content/Depth (15/30) PCS3 key questions:

• What protein of the RTC complex is targeted

– structure and function (relate back to literature review)?

• What other inhibitors are known (if any) for this protein?

• How is this protein be targeted (molecular mechanism)?

• What are the steps to be taken to develop an inhibitor (adaptation of existing methodology allowed but this needs to be cited and can’t just be copied)?

• How is the inhibitor being tested (ie binding studies, cell/human studies etc)?

• What is the process of optimisation of the inhibitor?

PCS4 key questions:

• What molecule(s)/principle(s) is/are being used for testing and why (relate back to molecular details/mechanisms of chosen cancer)?

• What other testing methods are known (if any) for this cancer type?

• What are the steps to be taken to develop a testing method (adaptation of existing methodology allowed but this needs to be cited and can’t just be copied)?

• How will the testing method be evaluated (ie shown that it actually works)?

• What is the process of optimisation of the testing method?

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